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Dhanaraju, M. D.
- Synthesis, Characterization and Anti-Microbial Evaluation of Derivative of Chalcone
Abstract Views :184 |
PDF Views:1
Authors
C. Gopi
1,
M. D. Dhanaraju
1
Affiliations
1 Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, IN
1 Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 2 (2011), Pagination: 181-182Abstract
To development of antimicrobial agents a series of chalcones were prepared by condensation of appropriate acetophenones with different aromatic aldehyde in the presence of alkali at 37oC. The synthesized compounds were characterized by IR, NMR spectral studies. The synthesized compounds were evaluated for anti-bacterial activity, and anti-fungal activity. The result had shown that anti-bacterial and anti-fungal activity of Compound containing electron withdrawing group (G2, G4, and G6).
Keywords
Chalcone, Aromatic Aldehyde, Acetophenone, Anti-Bacterial, Anti-Fungal.- Spectrophotometric Determination of Atorvastatin in Pharmaceutical Formulations
Abstract Views :199 |
PDF Views:1
Authors
Affiliations
1 Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, IN
1 Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 895-897Abstract
Rapid, simple and sensitive spectrophotometric methods (A&B) have been developed for the determination of Atorvastatin (ATN) in pharmaceutical bulk and tablet dosage form. Method A is based on the reaction of ATN with 3-methyl-2-benzothiazolinone hydrazone and ferric chloride to form green colored chromogen. Method B is based on the formation of wine red colored chromogen with 1,2-naphthaquinone-4-sulphonate and NaOH. The absorbances of the chromogens were measured at their respective wavelengths of maximum absorbance against the corresponding reagent blank. The proposed methods have been successfully applied to the analysis of the bulk drug and its tablet dosage form. The methods have been statistically evaluated and were found to be precise and accurate.Keywords
Atorvastatin, 3-Methyl-2-Benzothiazolinone Hydrazone, Ferric Chloride, 1, 2-Naphthaquinone-4-Sulphonate, Sodium Hydroxide.- Spectrophotometric Determination of Nadolol in Bulk and Pharmaceutical Formulations
Abstract Views :171 |
PDF Views:0
Authors
Affiliations
1 Research Lab, GIET School of Pharmacy, NH-5 Chaitanya Nagar, Rajahmundry-533294, IN
1 Research Lab, GIET School of Pharmacy, NH-5 Chaitanya Nagar, Rajahmundry-533294, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 1038-1040Abstract
Rapid, simple and sensitive spectrophotometric method has been developed for the determination of Nadolol in pharmaceutical bulk and tablet dosage forms. Method is based on the reaction of Nadolol with Sodium Nitropruside, Hydroxyl amine and sodium carbonate, to form light green colored chromogen. The colored species has absorption maximum at 440 nm and obeys Beer's law in the concentration range of 0.1-0.3 mg/ml. The optimum experimental parameters for the experiment have been studied. The proposed methods have been successfully applied to the analysis of the bulk drug and its tablet dosage form. Statistical analysis of the results has been carried out revealing high accuracy and good precision.Keywords
Nadolol, Sodium Nitropruside, Hydroxyl Amine HCl, Na2CO3.- A Simultaneous Estimation of Perindopril and Losartan in Solid Dosage Forms by UV Spectrophotometry
Abstract Views :182 |
PDF Views:0
Authors
Affiliations
1 Research Lab., GIET School of Pharmacy, NH-5 Chaitanya Nagar, Rajahmundry-533294, IN
1 Research Lab., GIET School of Pharmacy, NH-5 Chaitanya Nagar, Rajahmundry-533294, IN